منابع مشابه
Expression of cyclooxygenase-2 in melanocytic skin lesions by immunohistochemistry
Introduction: cyclooxygenase-2 (COX-2) is involved in pathogenesis of various tumors and possibly malignant skin tumors including malignant melanoma; however, there is not enough information about COX-2 expression in benign melanocytic lesions. In the present study we compared the expression levels of COX-2 in malignant melanoma and benign melanocytic lesions. Method: In this analytical study, ...
متن کاملExpression of calcyclin in human melanocytic lesions.
When comparing two subsequent stages of melanocytic tumor progression we identified calcyclin as a new potential progression marker, the expression of which was correlated with metastatic behavior of various human melanoma cell lines in nude mice. In this study, we describe a good correlation between RNA and protein levels in the xenografts of these cell lines and extended these experiments to ...
متن کاملIMP-3 expression in melanocytic lesions.
BACKGROUND Insulin-like growth factor-II mRNA-binding protein 3 (IMP-3 ), a member of the insulin-like growth factor mRNA-binding protein family, is expressed in several human malignancies, including melanomas. However, the expression of IMP-3 has not been explored in melanoma in situ, various histologic subtypes of invasive melanomas and atypical Spitz tumors. METHODS IMP-3 immunostain was p...
متن کاملA comparative study of estrogen receptor beta expression in melanoma and benign melanocytic lesions
Background: Malignant melanoma is the most aggressive form of skin cancer. In contrast to other tumors, the role of estrogen in the initiation and progression of melanoma remains unclear. The aim of this study was to evaluate estrogen receptor beta protein expression in human melanoma tissues and in the benign melanocytic lesions. Method: Twenty-one patients, 11 with cutaneous melanoma and 10 w...
متن کاملMelanocytic Lesions in Children
During the last general assembly of our society, held in Miami on February 2010, the election of the new IDS representatives took place. Our president, Peter Soyer, expressed his intention to resign from his role as president and the assembly agreed to give to myself the responsibility to continue his action. Iris Zalaudek was designated to be the new general secretary and Rainer Hofmann-Wellen...
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ژورنال
عنوان ژورنال: Human Pathology
سال: 2011
ISSN: 0046-8177
DOI: 10.1016/j.humpath.2010.10.022